Prediction of quaternary assembly of SARS coronavirus peplomer
Identifieur interne : 001566 ( Pmc/Checkpoint ); précédent : 001565; suivant : 001567Prediction of quaternary assembly of SARS coronavirus peplomer
Auteurs : Andrea Bernini [Italie] ; Ottavia Spiga [Italie] ; Arianna Ciutti [Italie] ; Stefano Chiellini [Italie] ; Luisa Bracci [Italie] ; Xiyun Yan [République populaire de Chine] ; Bojian Zheng [République populaire de Chine] ; Jiandong Huang [République populaire de Chine] ; Ming-Liang He [République populaire de Chine] ; Huai-Dong Song [République populaire de Chine] ; Pei Hao [République populaire de Chine] ; Guoping Zhao [République populaire de Chine] ; Neri Niccolai [Italie]Source :
- Biochemical and Biophysical Research Communications [ 0006-291X ] ; 2004.
Abstract
The tertiary structures of the S1 and S2 domains of the spike protein of the coronavirus which is responsible of the severe acute respiratory syndrome (SARS) have been recently predicted. Here a molecular assembly of SARS coronavirus peplomer which accounts for the available functional data is suggested. The interaction between S1 and S2 appears to be stabilised by a large hydrophobic network of aromatic side chains present in both domains. This feature results to be common to all coronaviruses, suggesting potential targeting for drugs preventing coronavirus-related infections.
Url:
DOI: 10.1016/j.bbrc.2004.10.156
PubMed: 15555555
PubMed Central: 7092937
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
PMC:7092937Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Prediction of quaternary assembly of SARS coronavirus peplomer</title><author><name sortKey="Bernini, Andrea" sort="Bernini, Andrea" uniqKey="Bernini A" first="Andrea" last="Bernini">Andrea Bernini</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena</wicri:regionArea><wicri:noRegion>I-53100 Siena</wicri:noRegion></affiliation></author><author><name sortKey="Spiga, Ottavia" sort="Spiga, Ottavia" uniqKey="Spiga O" first="Ottavia" last="Spiga">Ottavia Spiga</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena</wicri:regionArea><wicri:noRegion>I-53100 Siena</wicri:noRegion></affiliation></author><author><name sortKey="Ciutti, Arianna" sort="Ciutti, Arianna" uniqKey="Ciutti A" first="Arianna" last="Ciutti">Arianna Ciutti</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena</wicri:regionArea><wicri:noRegion>I-53100 Siena</wicri:noRegion></affiliation></author><author><name sortKey="Chiellini, Stefano" sort="Chiellini, Stefano" uniqKey="Chiellini S" first="Stefano" last="Chiellini">Stefano Chiellini</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena</wicri:regionArea><wicri:noRegion>I-53100 Siena</wicri:noRegion></affiliation></author><author><name sortKey="Bracci, Luisa" sort="Bracci, Luisa" uniqKey="Bracci L" first="Luisa" last="Bracci">Luisa Bracci</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena</wicri:regionArea><wicri:noRegion>I-53100 Siena</wicri:noRegion></affiliation></author><author><name sortKey="Yan, Xiyun" sort="Yan, Xiyun" uniqKey="Yan X" first="Xiyun" last="Yan">Xiyun Yan</name><affiliation wicri:level="3"><nlm:aff id="aff2">National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zheng, Bojian" sort="Zheng, Bojian" uniqKey="Zheng B" first="Bojian" last="Zheng">Bojian Zheng</name><affiliation wicri:level="1"><nlm:aff id="aff3">Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea><wicri:noRegion>Hong Kong</wicri:noRegion></affiliation></author><author><name sortKey="Huang, Jiandong" sort="Huang, Jiandong" uniqKey="Huang J" first="Jiandong" last="Huang">Jiandong Huang</name><affiliation wicri:level="1"><nlm:aff id="aff4">Department of Biochemistry, The University of Hong Kong, Pokfulam, Hong Kong, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Biochemistry, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea><wicri:noRegion>Hong Kong</wicri:noRegion></affiliation></author><author><name sortKey="He, Ming Liang" sort="He, Ming Liang" uniqKey="He M" first="Ming-Liang" last="He">Ming-Liang He</name><affiliation wicri:level="1"><nlm:aff id="aff5">Institute of Molecular Biology, The University of Hong Kong, Pokfulam, Hong Kong, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Molecular Biology, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea><wicri:noRegion>Hong Kong</wicri:noRegion></affiliation></author><author><name sortKey="Song, Huai Dong" sort="Song, Huai Dong" uniqKey="Song H" first="Huai-Dong" last="Song">Huai-Dong Song</name><affiliation wicri:level="1"><nlm:aff id="aff6">State Key Laboratory for Medical Genomics, Shanghai, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory for Medical Genomics, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Hao, Pei" sort="Hao, Pei" uniqKey="Hao P" first="Pei" last="Hao">Pei Hao</name><affiliation wicri:level="1"><nlm:aff id="aff7">Shanghai Center for Bioinformation Technology, Shanghai, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Shanghai Center for Bioinformation Technology, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Zhao, Guoping" sort="Zhao, Guoping" uniqKey="Zhao G" first="Guoping" last="Zhao">Guoping Zhao</name><affiliation wicri:level="1"><nlm:aff id="aff8">Chinese National Human Genome Center at Shanghai, Shanghai, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Chinese National Human Genome Center at Shanghai, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Niccolai, Neri" sort="Niccolai, Neri" uniqKey="Niccolai N" first="Neri" last="Niccolai">Neri Niccolai</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena</wicri:regionArea><wicri:noRegion>I-53100 Siena</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">15555555</idno><idno type="pmc">7092937</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092937</idno><idno type="RBID">PMC:7092937</idno><idno type="doi">10.1016/j.bbrc.2004.10.156</idno><date when="2004">2004</date><idno type="wicri:Area/Pmc/Corpus">000E24</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000E24</idno><idno type="wicri:Area/Pmc/Curation">000E24</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000E24</idno><idno type="wicri:Area/Pmc/Checkpoint">001566</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001566</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Prediction of quaternary assembly of SARS coronavirus peplomer</title><author><name sortKey="Bernini, Andrea" sort="Bernini, Andrea" uniqKey="Bernini A" first="Andrea" last="Bernini">Andrea Bernini</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena</wicri:regionArea><wicri:noRegion>I-53100 Siena</wicri:noRegion></affiliation></author><author><name sortKey="Spiga, Ottavia" sort="Spiga, Ottavia" uniqKey="Spiga O" first="Ottavia" last="Spiga">Ottavia Spiga</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena</wicri:regionArea><wicri:noRegion>I-53100 Siena</wicri:noRegion></affiliation></author><author><name sortKey="Ciutti, Arianna" sort="Ciutti, Arianna" uniqKey="Ciutti A" first="Arianna" last="Ciutti">Arianna Ciutti</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena</wicri:regionArea><wicri:noRegion>I-53100 Siena</wicri:noRegion></affiliation></author><author><name sortKey="Chiellini, Stefano" sort="Chiellini, Stefano" uniqKey="Chiellini S" first="Stefano" last="Chiellini">Stefano Chiellini</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena</wicri:regionArea><wicri:noRegion>I-53100 Siena</wicri:noRegion></affiliation></author><author><name sortKey="Bracci, Luisa" sort="Bracci, Luisa" uniqKey="Bracci L" first="Luisa" last="Bracci">Luisa Bracci</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena</wicri:regionArea><wicri:noRegion>I-53100 Siena</wicri:noRegion></affiliation></author><author><name sortKey="Yan, Xiyun" sort="Yan, Xiyun" uniqKey="Yan X" first="Xiyun" last="Yan">Xiyun Yan</name><affiliation wicri:level="3"><nlm:aff id="aff2">National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zheng, Bojian" sort="Zheng, Bojian" uniqKey="Zheng B" first="Bojian" last="Zheng">Bojian Zheng</name><affiliation wicri:level="1"><nlm:aff id="aff3">Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea><wicri:noRegion>Hong Kong</wicri:noRegion></affiliation></author><author><name sortKey="Huang, Jiandong" sort="Huang, Jiandong" uniqKey="Huang J" first="Jiandong" last="Huang">Jiandong Huang</name><affiliation wicri:level="1"><nlm:aff id="aff4">Department of Biochemistry, The University of Hong Kong, Pokfulam, Hong Kong, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Biochemistry, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea><wicri:noRegion>Hong Kong</wicri:noRegion></affiliation></author><author><name sortKey="He, Ming Liang" sort="He, Ming Liang" uniqKey="He M" first="Ming-Liang" last="He">Ming-Liang He</name><affiliation wicri:level="1"><nlm:aff id="aff5">Institute of Molecular Biology, The University of Hong Kong, Pokfulam, Hong Kong, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Molecular Biology, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea><wicri:noRegion>Hong Kong</wicri:noRegion></affiliation></author><author><name sortKey="Song, Huai Dong" sort="Song, Huai Dong" uniqKey="Song H" first="Huai-Dong" last="Song">Huai-Dong Song</name><affiliation wicri:level="1"><nlm:aff id="aff6">State Key Laboratory for Medical Genomics, Shanghai, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory for Medical Genomics, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Hao, Pei" sort="Hao, Pei" uniqKey="Hao P" first="Pei" last="Hao">Pei Hao</name><affiliation wicri:level="1"><nlm:aff id="aff7">Shanghai Center for Bioinformation Technology, Shanghai, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Shanghai Center for Bioinformation Technology, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Zhao, Guoping" sort="Zhao, Guoping" uniqKey="Zhao G" first="Guoping" last="Zhao">Guoping Zhao</name><affiliation wicri:level="1"><nlm:aff id="aff8">Chinese National Human Genome Center at Shanghai, Shanghai, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Chinese National Human Genome Center at Shanghai, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Niccolai, Neri" sort="Niccolai, Neri" uniqKey="Niccolai N" first="Neri" last="Niccolai">Neri Niccolai</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena</wicri:regionArea><wicri:noRegion>I-53100 Siena</wicri:noRegion></affiliation></author></analytic><series><title level="j">Biochemical and Biophysical Research Communications</title><idno type="ISSN">0006-291X</idno><idno type="eISSN">1090-2104</idno><imprint><date when="2004">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The tertiary structures of the S1 and S2 domains of the spike protein of the coronavirus which is responsible of the severe acute respiratory syndrome (SARS) have been recently predicted. Here a molecular assembly of SARS coronavirus peplomer which accounts for the available functional data is suggested. The interaction between S1 and S2 appears to be stabilised by a large hydrophobic network of aromatic side chains present in both domains. This feature results to be common to all coronaviruses, suggesting potential targeting for drugs preventing coronavirus-related infections.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Brown, E G" uniqKey="Brown E">E.G. Brown</name></author><author><name sortKey="Tetro, J A" uniqKey="Tetro J">J.A. Tetro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, H" uniqKey="Yang H">H. Yang</name></author><author><name sortKey="Yang, M" uniqKey="Yang M">M. Yang</name></author><author><name sortKey="Ding, Y" uniqKey="Ding Y">Y. Ding</name></author><author><name sortKey="Liu, Y" uniqKey="Liu Y">Y. Liu</name></author><author><name sortKey="Lou, Z" uniqKey="Lou Z">Z. Lou</name></author><author><name sortKey="Zhou, Z" uniqKey="Zhou Z">Z. Zhou</name></author><author><name sortKey="Sun, L" uniqKey="Sun L">L. Sun</name></author><author><name sortKey="Mo, L" uniqKey="Mo L">L. Mo</name></author><author><name sortKey="Ye, S" uniqKey="Ye S">S. Ye</name></author><author><name sortKey="Pang, H" uniqKey="Pang H">H. Pang</name></author><author><name sortKey="Gao, G F" uniqKey="Gao G">G.F. Gao</name></author><author><name sortKey="Anand, K" uniqKey="Anand K">K. Anand</name></author><author><name sortKey="Bartlam, M" uniqKey="Bartlam M">M. Bartlam</name></author><author><name sortKey="Hilgenfeld, R" uniqKey="Hilgenfeld R">R. Hilgenfeld</name></author><author><name sortKey="Rao, Z" uniqKey="Rao Z">Z. Rao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Egloff, M P" uniqKey="Egloff M">M.P. Egloff</name></author><author><name sortKey="Ferron, F" uniqKey="Ferron F">F. Ferron</name></author><author><name sortKey="Campanacci, V" uniqKey="Campanacci V">V. Campanacci</name></author><author><name sortKey="Longhi, S" uniqKey="Longhi S">S. Longhi</name></author><author><name sortKey="Rancurel, C" uniqKey="Rancurel C">C. Rancurel</name></author><author><name sortKey="Dutartre, H" uniqKey="Dutartre H">H. Dutartre</name></author><author><name sortKey="Snijder, E J" uniqKey="Snijder E">E.J. Snijder</name></author><author><name sortKey="Gorbalenya, A E" uniqKey="Gorbalenya A">A.E. Gorbalenya</name></author><author><name sortKey="Cambillau, C" uniqKey="Cambillau C">C. Cambillau</name></author><author><name sortKey="Canard, B" uniqKey="Canard B">B. Canard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shen, X" uniqKey="Shen X">X. Shen</name></author><author><name sortKey="Xue, J H" uniqKey="Xue J">J.H. Xue</name></author><author><name sortKey="Yu, C Y" uniqKey="Yu C">C.Y. Yu</name></author><author><name sortKey="Luo, H B" uniqKey="Luo H">H.B. Luo</name></author><author><name sortKey="Qin, L" uniqKey="Qin L">L. Qin</name></author><author><name sortKey="Yu, X J" uniqKey="Yu X">X.J. Yu</name></author><author><name sortKey="Chen, J" uniqKey="Chen J">J. Chen</name></author><author><name sortKey="Chen, L L" uniqKey="Chen L">L.L. Chen</name></author><author><name sortKey="Xiong, B" uniqKey="Xiong B">B. Xiong</name></author><author><name sortKey="Yue, L D" uniqKey="Yue L">L.D. Yue</name></author><author><name sortKey="Cai, J H" uniqKey="Cai J">J.H. Cai</name></author><author><name sortKey="Shen, J H" uniqKey="Shen J">J.H. Shen</name></author><author><name sortKey="Luo, X M" uniqKey="Luo X">X.M. Luo</name></author><author><name sortKey="Chen, K X" uniqKey="Chen K">K.X. Chen</name></author><author><name sortKey="Shi, T L" uniqKey="Shi T">T.L. Shi</name></author><author><name sortKey="Li, Y X" uniqKey="Li Y">Y.X. Li</name></author><author><name sortKey="Hu, G X" uniqKey="Hu G">G.X. Hu</name></author><author><name sortKey="Jiang, H L" uniqKey="Jiang H">H.L. Jiang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Spiga, O" uniqKey="Spiga O">O. Spiga</name></author><author><name sortKey="Bernini, A" uniqKey="Bernini A">A. Bernini</name></author><author><name sortKey="Ciutti, A" uniqKey="Ciutti A">A. Ciutti</name></author><author><name sortKey="Chiellini, S" uniqKey="Chiellini S">S. Chiellini</name></author><author><name sortKey="Menciassi, N" uniqKey="Menciassi N">N. Menciassi</name></author><author><name sortKey="Finetti, F" uniqKey="Finetti F">F. Finetti</name></author><author><name sortKey="Causarono, V" uniqKey="Causarono V">V. Causarono</name></author><author><name sortKey="Anselmi, F" uniqKey="Anselmi F">F. Anselmi</name></author><author><name sortKey="Prischi, F" uniqKey="Prischi F">F. Prischi</name></author><author><name sortKey="Niccolai, N" uniqKey="Niccolai N">N. Niccolai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xu, X" uniqKey="Xu X">X. Xu</name></author><author><name sortKey="Liu, Y" uniqKey="Liu Y">Y. Liu</name></author><author><name sortKey="Weiss, S" uniqKey="Weiss S">S. Weiss</name></author><author><name sortKey="Arnold, E" uniqKey="Arnold E">E. Arnold</name></author><author><name sortKey="Sarafianos, S G" uniqKey="Sarafianos S">S.G. Sarafianos</name></author><author><name sortKey="Ding, J" uniqKey="Ding J">J. Ding</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cavanagh, D" uniqKey="Cavanagh D">D. Cavanagh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, Y" uniqKey="Lin Y">Y. Lin</name></author><author><name sortKey="Yan, X" uniqKey="Yan X">X. Yan</name></author><author><name sortKey="Cao, W" uniqKey="Cao W">W. Cao</name></author><author><name sortKey="Wang, C" uniqKey="Wang C">C. Wang</name></author><author><name sortKey="Feng, J" uniqKey="Feng J">J. Feng</name></author><author><name sortKey="Duan, J" uniqKey="Duan J">J. Duan</name></author><author><name sortKey="Xie, S" uniqKey="Xie S">S. Xie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Groot, R J" uniqKey="De Groot R">R.J. de Groot</name></author><author><name sortKey="Luytjes, W" uniqKey="Luytjes W">W. Luytjes</name></author><author><name sortKey="Horzinek, M C" uniqKey="Horzinek M">M.C. Horzinek</name></author><author><name sortKey="Van Der Zeijst, B A" uniqKey="Van Der Zeijst B">B.A. van der Zeijst</name></author><author><name sortKey="Spaan, W J" uniqKey="Spaan W">W.J. Spaan</name></author><author><name sortKey="Lenstra, J A" uniqKey="Lenstra J">J.A. Lenstra</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Berman, H M" uniqKey="Berman H">H.M. Berman</name></author><author><name sortKey="Westbrook, J" uniqKey="Westbrook J">J. Westbrook</name></author><author><name sortKey="Feng, Z" uniqKey="Feng Z">Z. Feng</name></author><author><name sortKey="Gilliland, G" uniqKey="Gilliland G">G. Gilliland</name></author><author><name sortKey="Bhat, T N" uniqKey="Bhat T">T.N. Bhat</name></author><author><name sortKey="Weissig, H" uniqKey="Weissig H">H. Weissig</name></author><author><name sortKey="Shindyalov, I N" uniqKey="Shindyalov I">I.N. Shindyalov</name></author><author><name sortKey="Bourne, P E" uniqKey="Bourne P">P.E. Bourne</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sippl, M J" uniqKey="Sippl M">M.J. Sippl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Berendsen, H J C" uniqKey="Berendsen H">H.J.C. Berendsen</name></author><author><name sortKey="Van Der Spoel, D" uniqKey="Van Der Spoel D">D. van der Spoel</name></author><author><name sortKey="Van Drunen, R" uniqKey="Van Drunen R">R. van Drunen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Koradi, R" uniqKey="Koradi R">R. Koradi</name></author><author><name sortKey="Billeter, M" uniqKey="Billeter M">M. Billeter</name></author><author><name sortKey="Wuthrich, K" uniqKey="Wuthrich K">K. Wuthrich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lewicki, D N" uniqKey="Lewicki D">D.N. Lewicki</name></author><author><name sortKey="Gallagher, T M" uniqKey="Gallagher T">T.M. Gallagher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, S K" uniqKey="Wong S">S.K. Wong</name></author><author><name sortKey="Li, W" uniqKey="Li W">W. Li</name></author><author><name sortKey="Moore, M J" uniqKey="Moore M">M.J. Moore</name></author><author><name sortKey="Choe, H" uniqKey="Choe H">H. Choe</name></author><author><name sortKey="Farzan, M" uniqKey="Farzan M">M. Farzan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thompson, J D" uniqKey="Thompson J">J.D. Thompson</name></author><author><name sortKey="Higgins, D G" uniqKey="Higgins D">D.G. Higgins</name></author><author><name sortKey="Gibson, T J" uniqKey="Gibson T">T.J. Gibson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sauter, N K" uniqKey="Sauter N">N.K. Sauter</name></author><author><name sortKey="Hanson, J E" uniqKey="Hanson J">J.E. Hanson</name></author><author><name sortKey="Glick, G D" uniqKey="Glick G">G.D. Glick</name></author><author><name sortKey="Brown, J H" uniqKey="Brown J">J.H. Brown</name></author><author><name sortKey="Crowther, R L" uniqKey="Crowther R">R.L. Crowther</name></author><author><name sortKey="Park, S J" uniqKey="Park S">S.J. Park</name></author><author><name sortKey="Skehel, J J" uniqKey="Skehel J">J.J. Skehel</name></author><author><name sortKey="Wiley, D C" uniqKey="Wiley D">D.C. Wiley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Delmas, B" uniqKey="Delmas B">B. Delmas</name></author><author><name sortKey="Laude, H" uniqKey="Laude H">H. Laude</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wolf, E" uniqKey="Wolf E">E. Wolf</name></author><author><name sortKey="Kim, P S" uniqKey="Kim P">P.S. Kim</name></author><author><name sortKey="Berger, B" uniqKey="Berger B">B. Berger</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Kyte, J" uniqKey="Kyte J">J. Kyte</name></author><author><name sortKey="Doolittle, R F" uniqKey="Doolittle R">R.F. Doolittle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhu, J" uniqKey="Zhu J">J. Zhu</name></author><author><name sortKey="Xiao, G" uniqKey="Xiao G">G. Xiao</name></author><author><name sortKey="Xu, Y" uniqKey="Xu Y">Y. Xu</name></author><author><name sortKey="Yuan, F" uniqKey="Yuan F">F. Yuan</name></author><author><name sortKey="Zheng, C" uniqKey="Zheng C">C. Zheng</name></author><author><name sortKey="Liu, Y" uniqKey="Liu Y">Y. Liu</name></author><author><name sortKey="Yan, H" uniqKey="Yan H">H. Yan</name></author><author><name sortKey="Cole, D K" uniqKey="Cole D">D.K. Cole</name></author><author><name sortKey="Bell, J I" uniqKey="Bell J">J.I. Bell</name></author><author><name sortKey="Rao, Z" uniqKey="Rao Z">Z. Rao</name></author><author><name sortKey="Tien, P" uniqKey="Tien P">P. Tien</name></author><author><name sortKey="Gao, G F" uniqKey="Gao G">G.F. Gao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, S" uniqKey="Liu S">S. Liu</name></author><author><name sortKey="Xiao, G" uniqKey="Xiao G">G. Xiao</name></author><author><name sortKey="Chen, Y" uniqKey="Chen Y">Y. Chen</name></author><author><name sortKey="He, Y" uniqKey="He Y">Y. He</name></author><author><name sortKey="Niu, J" uniqKey="Niu J">J. Niu</name></author><author><name sortKey="Escalante, C R" uniqKey="Escalante C">C.R. Escalante</name></author><author><name sortKey="Xiong, H" uniqKey="Xiong H">H. Xiong</name></author><author><name sortKey="Farmar, J" uniqKey="Farmar J">J. Farmar</name></author><author><name sortKey="Debnath, A K" uniqKey="Debnath A">A.K. Debnath</name></author><author><name sortKey="Tien, P" uniqKey="Tien P">P. Tien</name></author><author><name sortKey="Jiang, S" uniqKey="Jiang S">S. Jiang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xu, Y" uniqKey="Xu Y">Y. Xu</name></author><author><name sortKey="Liu, Y" uniqKey="Liu Y">Y. Liu</name></author><author><name sortKey="Lou, Z" uniqKey="Lou Z">Z. Lou</name></author><author><name sortKey="Qin, L" uniqKey="Qin L">L. Qin</name></author><author><name sortKey="Li, X" uniqKey="Li X">X. Li</name></author><author><name sortKey="Bai, Z" uniqKey="Bai Z">Z. Bai</name></author><author><name sortKey="Pang, H" uniqKey="Pang H">H. Pang</name></author><author><name sortKey="Tien, P" uniqKey="Tien P">P. Tien</name></author><author><name sortKey="Gao, G F" uniqKey="Gao G">G.F. Gao</name></author><author><name sortKey="Rao, Z" uniqKey="Rao Z">Z. Rao</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Biochem Biophys Res Commun</journal-id><journal-id journal-id-type="iso-abbrev">Biochem. Biophys. Res. Commun</journal-id><journal-title-group><journal-title>Biochemical and Biophysical Research Communications</journal-title></journal-title-group><issn pub-type="ppub">0006-291X</issn><issn pub-type="epub">1090-2104</issn><publisher><publisher-name>Elsevier Inc.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">15555555</article-id><article-id pub-id-type="pmc">7092937</article-id><article-id pub-id-type="publisher-id">S0006-291X(04)02463-5</article-id><article-id pub-id-type="doi">10.1016/j.bbrc.2004.10.156</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Prediction of quaternary assembly of SARS coronavirus peplomer</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Bernini</surname><given-names>Andrea</given-names></name><xref rid="aff1" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Spiga</surname><given-names>Ottavia</given-names></name><xref rid="aff1" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Ciutti</surname><given-names>Arianna</given-names></name><xref rid="aff1" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Chiellini</surname><given-names>Stefano</given-names></name><xref rid="aff1" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Bracci</surname><given-names>Luisa</given-names></name><xref rid="aff1" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Yan</surname><given-names>Xiyun</given-names></name><xref rid="aff2" ref-type="aff">b</xref></contrib><contrib contrib-type="author"><name><surname>Zheng</surname><given-names>Bojian</given-names></name><xref rid="aff3" ref-type="aff">c</xref></contrib><contrib contrib-type="author"><name><surname>Huang</surname><given-names>Jiandong</given-names></name><xref rid="aff4" ref-type="aff">d</xref></contrib><contrib contrib-type="author"><name><surname>He</surname><given-names>Ming-Liang</given-names></name><xref rid="aff5" ref-type="aff">e</xref></contrib><contrib contrib-type="author"><name><surname>Song</surname><given-names>Huai-Dong</given-names></name><xref rid="aff6" ref-type="aff">f</xref></contrib><contrib contrib-type="author"><name><surname>Hao</surname><given-names>Pei</given-names></name><xref rid="aff7" ref-type="aff">g</xref></contrib><contrib contrib-type="author"><name><surname>Zhao</surname><given-names>Guoping</given-names></name><xref rid="aff8" ref-type="aff">h</xref></contrib><contrib contrib-type="author"><name><surname>Niccolai</surname><given-names>Neri</given-names></name><email>niccolai@unisi.it</email><xref rid="aff1" ref-type="aff">a</xref><xref rid="cor1" ref-type="corresp">*</xref></contrib></contrib-group><aff id="aff1"><label>a</label>Department of Molecular Biology, Biomolecular Structure Research Center, University of Siena, I-53100 Siena, Italy</aff><aff id="aff2"><label>b</label>National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China</aff><aff id="aff3"><label>c</label>Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, China</aff><aff id="aff4"><label>d</label>Department of Biochemistry, The University of Hong Kong, Pokfulam, Hong Kong, China</aff><aff id="aff5"><label>e</label>Institute of Molecular Biology, The University of Hong Kong, Pokfulam, Hong Kong, China</aff><aff id="aff6"><label>f</label>State Key Laboratory for Medical Genomics, Shanghai, China</aff><aff id="aff7"><label>g</label>Shanghai Center for Bioinformation Technology, Shanghai, China</aff><aff id="aff8"><label>h</label>Chinese National Human Genome Center at Shanghai, Shanghai, China</aff><author-notes><corresp id="cor1"><label>*</label>Corresponding author. Fax: +39 577 234903 <email>niccolai@unisi.it</email></corresp></author-notes><pub-date pub-type="pmc-release"><day>11</day><month>11</month><year>2004</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><day>24</day><month>12</month><year>2004</year></pub-date><pub-date pub-type="epub"><day>11</day><month>11</month><year>2004</year></pub-date><volume>325</volume><issue>4</issue><fpage>1210</fpage><lpage>1214</lpage><history><date date-type="received"><day>13</day><month>10</month><year>2004</year></date></history><permissions><copyright-statement>Copyright © 2004 Elsevier Inc. All rights reserved.</copyright-statement><copyright-year>2004</copyright-year><copyright-holder>Elsevier Inc.</copyright-holder><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions><abstract><p>The tertiary structures of the S1 and S2 domains of the spike protein of the coronavirus which is responsible of the severe acute respiratory syndrome (SARS) have been recently predicted. Here a molecular assembly of SARS coronavirus peplomer which accounts for the available functional data is suggested. The interaction between S1 and S2 appears to be stabilised by a large hydrophobic network of aromatic side chains present in both domains. This feature results to be common to all coronaviruses, suggesting potential targeting for drugs preventing coronavirus-related infections.</p></abstract><kwd-group><title>Keywords</title><kwd>SARS coronavirus</kwd><kwd>Spike glycoprotein</kwd><kwd>Quaternary structure prediction</kwd></kwd-group></article-meta></front></pmc><affiliations><list><country><li>Italie</li><li>République populaire de Chine</li></country><settlement><li>Pékin</li></settlement></list><tree><country name="Italie"><noRegion><name sortKey="Bernini, Andrea" sort="Bernini, Andrea" uniqKey="Bernini A" first="Andrea" last="Bernini">Andrea Bernini</name></noRegion><name sortKey="Bracci, Luisa" sort="Bracci, Luisa" uniqKey="Bracci L" first="Luisa" last="Bracci">Luisa Bracci</name><name sortKey="Chiellini, Stefano" sort="Chiellini, Stefano" uniqKey="Chiellini S" first="Stefano" last="Chiellini">Stefano Chiellini</name><name sortKey="Ciutti, Arianna" sort="Ciutti, Arianna" uniqKey="Ciutti A" first="Arianna" last="Ciutti">Arianna Ciutti</name><name sortKey="Niccolai, Neri" sort="Niccolai, Neri" uniqKey="Niccolai N" first="Neri" last="Niccolai">Neri Niccolai</name><name sortKey="Spiga, Ottavia" sort="Spiga, Ottavia" uniqKey="Spiga O" first="Ottavia" last="Spiga">Ottavia Spiga</name></country><country name="République populaire de Chine"><noRegion><name sortKey="Yan, Xiyun" sort="Yan, Xiyun" uniqKey="Yan X" first="Xiyun" last="Yan">Xiyun Yan</name></noRegion><name sortKey="Hao, Pei" sort="Hao, Pei" uniqKey="Hao P" first="Pei" last="Hao">Pei Hao</name><name sortKey="He, Ming Liang" sort="He, Ming Liang" uniqKey="He M" first="Ming-Liang" last="He">Ming-Liang He</name><name sortKey="Huang, Jiandong" sort="Huang, Jiandong" uniqKey="Huang J" first="Jiandong" last="Huang">Jiandong Huang</name><name sortKey="Song, Huai Dong" sort="Song, Huai Dong" uniqKey="Song H" first="Huai-Dong" last="Song">Huai-Dong Song</name><name sortKey="Zhao, Guoping" sort="Zhao, Guoping" uniqKey="Zhao G" first="Guoping" last="Zhao">Guoping Zhao</name><name sortKey="Zheng, Bojian" sort="Zheng, Bojian" uniqKey="Zheng B" first="Bojian" last="Zheng">Bojian Zheng</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Pmc/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001566 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd -nk 001566 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Pmc
|étape= Checkpoint
|type= RBID
|clé= PMC:7092937
|texte= Prediction of quaternary assembly of SARS coronavirus peplomer
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/RBID.i -Sk "pubmed:15555555" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |